Feng Zhang lab’s recent work published in Science introduces a novel algorithm, fast locality-sensitive hashing-based clustering (FLSHclust), designed for mining large sequencing databases. This approach aims to address the limitations of existing methods in...
The UK’s Medicines and Healthcare Regulatory Agency (MHRA) has granted approval for Casgevy, the world’s first gene therapy for sickle cell disease, utilizing the CRISPR gene-editing tool. This landmark decision could bring relief to thousands of...
RNA could be considered DNA’s younger sibling. From the very beginning, RNA’s milestones came later and attracted less attention than DNA’s milestones. For example, the discovery of DNA’s structure was first published in 1953; the corresponding discovery for RNA’s...
Researchers at Duke University have advanced cancer T-cell therapy using CRISPR for high-throughput screening of human immune cells. They discovered BATF3, a master regulator transcription factor gene, which reprograms thousands of genes in T cells, enhancing their...
Halloween brings to mind pumpkins and trick or treat, but for the 100,000 Americans suffering from sickle cell disease, this past October 31 had a different meaning when an FDA advisory panel deemed the first potentially curative SCD therapy safe enough for clinical...