PackGene provides preclinical grade plasmids that come with extensive and rigorous quality specifications and analysis, catering to all of your preclinical project requirements. They are perfectly suited for in vivo animal studies from mice to non-human primates, and are ideal for research use in gene therapy, cell therapy, and vaccine development. Quantities are available starting from 10 mg and beyond.

Comprehensive quality control of supercoil content and endotoxin levels

Animal- free production is available

Quantitative impurity analysis

Guaranteed quantity of mg to gram with material archiving option
PackGene plasmid process | Preclinical |
Clone screening | √ |
Growth condition optimization | √ |
High density fermentation | √ |
Alkaline lysis | √ |
Chromatographic purification | √ |
Antibiotics free | √ |
Consistent manufacturing process | √ |
Instrument calibration/validation | Calibration |
COA & CoC | COA |
TSE/BSE | O |


Test | Methods |
Appearance | Visual inspection |
A260:280 | Ultraviolet-visible spectrophotometry (A260/A280) |
Homogeneity | HPLC |
Restriction Analysis | Agarose gel |
Residual RNA | SYBRGold |
Residual E. coli DNA | qPCR |
Endotoxin | LAL |
Bioburden Testing | Direct inoculation |
Sequencing | Sanger |
Antibiotics Free Production | – |
Residual Host Protein | HCP ELISA |
Animal Free Production* | – |
Mycoplasma Contamination | qPCR |
Material Archiving | – |
pH | Potentiometry |
Kanamycin | ELISA |
Sterility | |
Osmolality |
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