2022 (updating)

[1] Guangxue Xu, Ran Zhang, Huapeng Li,Zhiyong Lou, et al. Structural basis for the neurotropic AAV9 and the engineered AAVPHP.eB recognition with cellular receptors. BioRxiv, 2022.  DOI: 



[1] Menglong Chen, Xiaoping Li, et al. In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers. Genome Medicine, 2021.(IF=10.675)  DOI: 

[2] Zongqin Xiang, Wen Li, Gong Chen, et al. Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex. Neural Regen Res 2021. (IF=3.171) DOI: 10.4103/1673-5374.295925 

[3] Tess Torregrosa, Sydney Lehman, Shih-Ching Lo, et al. Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice. Gene Therapy, 2021. (IF=4.128) DOI:

[4] Nan Li, Shixue Gou,Kepin Wang, et al. CRISPR / Cas9 -Mediated  Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I. Molecular Therapy, 2021. (IF=8.986) DOI:

[5] Jing Miao, Xiqin Yang, FuqiangHu, et al. Hepatocyte-targeting and microenvironmentally responsive glycolipid-like polymer micelles for gene therapy of hepatitis B. Molecular Therapy – Nucleic Acids 2021. (IF=7.032) DOI:

[6] Yong Yang,Yusi Peng, et al.Human ACE2‑Functionalized Gold “Virus‑Trap” Nanostructures for Accurate Capture of SARS‑CoV‑2 and Single‑Virus SERS Detection.Nanomicro Lett. 2021.(IF=12.2645)  DOI: 10.1007/s40820-021-00620-8

[7] Yingjun Li,Liu Cao, et al.Remdesivir Metabolite GS-441524 Effectively Inhibits SARS-CoV-2 Infection in Mouse Models.J Med Chem. 2021.(IF=6.205).  DOI: 10.1021/acs.jmedchem.0c01929

[8] Liu Z, Chen S, xie W, Song Y, Li J, Lai L, Li Z, Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9, Molecular Therapy. 2021 (IF=8.986), DOI: https://

[9] Daniel J. Apicco, Evgeny Shlevkov, et al. The Parkinson’s disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release. PNAS. 2021 (IF=9.412). DOI: 10.1073/pnas.2006476118

[10] Zhaowei Wu, Yifei Zhang and Quanjiang Ji , et al. Programmed genome editing by a miniature CRISPR-Cas12f nuclease. Nature Chemical Biology, 2021.  (IF=12.587) DOI:

[11] ShuaiLu, Xi-xiuXie and Rui-tianLiu , et al. The immunodominant and neutralization linear epitopes for SARS-CoV-2. Cell Reports, 2021.  (IF=8.109). DOI:

[12] Justin W. Nicholatos, Joost Groot and Andreas Weihofen, et al. SCD Inhibition Protects from α-Synuclein- Induced Neurotoxicity But Is Toxic to Early Neuron Cultures. eNeuro, 2021. (IF=3.317), DOI:

[13] Hubert D.-J. Daniel, Sanjay Kumar, Asha Mary Abraham et al. Prevalence of Adeno-Associated Virus 3 Capsid Binding and Neutralizing Antibodies in Healthy and Hemophilia B Individuals from India. Human Gene Therapy, 2021.(IF=4.51), DOI:

[14] Lijie Wang, Wei Xue, Hongxia Zhang,et al. Eliminating base -editor -induced genome -wide and transcriptome -wide off-target mutations. Nature Cell Biology, 2021. (IF=20.761). DOI: 

[15] XueYan Zhang, Jun Li, Cai-Juan Li,Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey. 2021. (IF=5.135). DOI: 10.4103/1673-5374.313056.

[16] Pete Clarner, Shukkwan K. Lau, et al. Development of a one-step RT-ddPCR method to determine the expression and potency of AAV vectors. Molecular therapy, 2021. DOI:

[17] Yi Pu, Russell Katz, Yunqiu Chen et al. Development and Application of a Liquid Chromatography Mass Spectrometry Method for Residual Iodixanol Quantification in AAV-Based Gene Therapy Product Development. Human Gene Therapy, 2021. DOI:

[18] Jinyu Kang, Lujie Huang, Aiming Liu et al. Promoter CAG is more efficient than hepatocyte‑targeting TBG for transgene expression via rAAV8 in liver tissues. Mol Med Rep. 2022. DOI 10.3892/mmr.2021.12532


[1] Farzaneh Moghadam, Ryan LeGraw, et al. Synthetic immunomodulation with a CRISPR super repressor in vivo[J]. Nature Cell Biology, 2020. (IF=20.042) DOI: 10.1038/s41556-020-0563-3

[2] Yue Qiu, Chaoqi Liang, Yuan Yao, et al. MicroRNA-20b Promotes Cardiac Hypertrophy by the Inhibition of Mitofusin 2-Mediated Inter-organelle Ca 2+ Cross-Talk[J]. Molecular therapy. Nucleic acids, 2020. (IF=7.032) DOI: 

[3] HyungJoo Kwon, Keyun Qing, et al. Adeno Associated Virus D Sequence Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene : Implications in the Development of Adeno Associated Virus Vectors for Modulating Humoral Immune Response[J]. Human Gene Therapy, 2020. (IF=4.273) DOI: 10.1089/hum.2020.018

[4] Di Chen,Qian Chen, Wenting Wang, et al. A Whole-Brain Cell-Type Specific Sparse Neuron Labeling Method and Its Application in a Shank3 Autistic Mouse Model[J]. Front Cell Neurosci, 2020. (IF=3.921) DOI: 10.3389/fncel.2020.00145

[5] Yingjun Li, Liu Cao, Deyin Guo, Xumu Zhang, et al. Remdesivir Metabolite GS-441524 Effectively Inhibits SARS-CoV2 Infection in Mouse Models. J Med Chem 2020. (IF=6.205) DOI: 10.1021/acs.jmedchem.0c01929

[6] Gen-Cheng Gong, Sheng-Ren Song, et al. Serpina3n is closely associated with fibrotic procession and knockdown ameliorates bleomycin induced pulmonary fibrosis. Biochem Biophys Res Commun. 2020 (IF=3.027) DOI: 10.1016/j.bbrc.2020.08.094

[7] Zhonghua Zhou, Ziyi Yang, Gong Zhang, et al. Temperature dependence of the SARS-CoV-2 affinity to human ACE2 determines COVID-19 progression and clinical outcome. CSBJ 2020. (IF=6.018)  Doi:

[8] Yinghua Huang, Hui Zhang,Baoming Qin et al. JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency. nature communications 2020. (IF=12.121)  DOI: 

[9] Gong Chen, Wen Li, et al. Comment on Rapid and efficient in vivo astrocyte -to- neuron conversion with regional identity and connectivity. 2020. bioRxiv,DOI:

[10] Lu S, Xi-Xiu Xie, et al. The immunodominant and neutralization linear epitopes for SARS-CoV-2. Cell Reports, 2020. DOI: 10.1016/j.celrep.2020.108666

[11] Hua Yang, Keyun Qing, Arun Srivastava,et al. Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vector Implications in Gene Therapy and Genome Editing[J].Human Gene Therapy, 2020. (IF=4.273) DOI: 10.1016/j.omtn.2020.03.009

[12] Hui-Ling Tang, Si-Yu Chen, Yue-Sheng Long, et al. Neurobiology-Expression Pattern of ALOXE3 in Mouse Brain Suggests Its Relationship with Seizure Susceptibility, Cellular and Molecular,2020. (IF=1.72) DOI: 


[1] Hans E. Anderson, Kristin L. Schaller, et al. Intravascular Injections of Adeno associated Viral Vector Serotypes rh10 and PHP.B Transduce Murine Sciatic Nerve Axons[J]. Neuroscience Letter, 2019. (IF=2.274)DOI: 10.1016/j.neulet.2019.05.010

[2] Baolin Guo, Jing Chen, Qian Chen, Wenting Wang, et al. Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice[J]. Nature Neuroscience, 2019.(IF=20.071) DOI:10.1038/s41593-019-0445-9

[3] Ran Zhang,ZhiyongLou, et al. Divergent engagements between adenoassociatedviruses with their cellular receptor AAVR[J]. Nature Communications, 2019.(IF=12.121)  DOI: 10.1038/s41467-019-11668-x

[4] XU, S. G YANG, et al. MiR-592 functions as a tumor suppressor in acute myeloid leukemia by targeting ROCK1 and predicts patients’ prognosis[J]. EUR REV MED PHARMACO, 2019. (IF=3.024) DOI: 10.26355/eurrev_201902_17120

[5] Yongwei Shu, Jie Yao, Yang Qu, et al. Intravenous injection of AAV-PHP.eB across the blood brain barrier in the adult mouse for central nervous system gene therapy[J] Oncology and Translational Medicine, 2019. DOI: 10.1007/s10330-018-0313-3