Citations
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Endogenous Sox2 expression is essential for Atoh1-induced hair cell addition and regeneration in the mouse utricle
Author:
Yu-Tong Yang, Jing-Ying Guo, Jun-Yi Xu, Wei- Su, Ming-Yu Hao, Ting Zhang, Shu-Sheng Gong, Guo-Peng Wang
Journal: Neuroscience
Doi: https://www.doi.org/10.1016/j.neuroscience.2026.03.051
Mar 31 2026 -
Human promoter-driven AAV tools enable precision gene therapy targeting cochlear hair cells
Author:
Liyan Zhang, Yicheng Lu, Xianmin Wu, Jinyi Fan, Xinru Zhang, Yang Xu, Hao Wei, Qiuhan Sun, Lulu Jiang, Huawei Tuo, Nianci Li, Hua Jin, Wu Cao, Beibei Ye, Ziyu Zhang, Yunkai Zhang, Fangyi Chen, Ling Lu, Jieyu Qi, Renjie Chai, Fangzhi Tan
Journal: Cell Reports Medicine
Doi: https://www.doi.org/10.1016/j.xcrm.2026.102725
Mar 31 2026 -
Identification Of a Therapeutic Threshold For AAV-STXBP1 Gene Therapy in a Rodent Model of STXBP1 Developmental & Epileptic Encephalopathy
Author:
Nicholas B. Gallo, John W. Annand, Pete Clarner, Brian Harvey, Elena Morozova, Christian Ehrenfels, Ting Jiang, Long Yuan, Samneet Kashyap, Xiaodong Lu, Jinkuk Choi, Jennifer Zoll, Anh Nhu, Ashton Brennecke, Purvish Patel, Davide Gianni, Edward Guilmette, Sarah Geisler, Adam Sheehy, Kevin Ghaemi, Sam Benezra, Ayan Ghoshal, Yuqing Liu, Thomas Carlile, Shaolong Cao, Fergal Casey, Samir Koirala, Sijia Wu
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.ymthe.2026.03.027
Mar 24 2026 -
Functional Evaluation of Computationally Designed IL-10 in IL-10 KO Mice
Author:
Jordan Stokes 1,Iram Hyder 1,Zhihang Shen 2ORCID,Peter Ramdhan 2ORCID,Allison Bayer 3,Clive Wasserfall 3,Chenglong Li 2,* andSihong Song 1,*
Journal: Biomolecules
Doi: https://www.doi.org/10.3390/biom16030482
Mar 23 2026 -
Template-independent genome editing and restoration for correcting frameshift disorders
Author:
Shiwei Qiu, Lian Liu, Bin Xiang, Ziqin Jin, Yahong Li, Dong Li, Hanqing Hou, Kuan Li, Gege Wei, Jiangping Xie, Shang Li, Shuang Liu, Chunlai Chen, Xin Liang, Qianwen Sun & Wei Xiong
Journal: Nature Biomedical Engineering
Doi: https://www.doi.org/10.1038/s41551-026-01635-5
Mar 23 2026 -
Multi-omics reveals the DR5-FXR-CHPT1 axis governs hepatocyte pyroptosis via glycerophospholipid remodeling after major partial hepatectomy
Author:
Hua Li, Yongsheng tang, XU LU, Xi Luo, Qinghai Lian, Yingqiu Song, Manqiu Kang, Zihan Qiao, Zhihua Rao, Linsen Ye, Zenan Yuan, Changchang JIA
Journal: Research Square
Doi: https://www.doi.org/10.21203/rs.3.rs-9039762/v1
Mar 20 2026 -
The eIF3a/m6A/ENO1 axis orchestrates glycolytic reprogramming and cell growth in cervical cancer
Author:
Riyangul Kurban, Jing Pan, Tusunggu Amar & Xiaoli Bo
Journal: Journal of Bioenergetics and Biomembranes
Doi: https://www.doi.org/10.1007/s10863-026-10096-z
Mar 18 2026 -
GPX3 activates autophagy to protect cochlear spiral ganglion neurons from injury in age-related hearing loss
Author:
Miaomiao An, Huan Yin, Yanan Li, Huan Cao, Zhidong Zhang, Jianwang Yang, Jiantao Wang, Tao Liu, Lei Zhao, Chen Wang, Ruoxiang Miao, Baoshan Wang
Journal: Free Radical Biology and Medicine
Doi: https://www.doi.org/10.1016/j.freeradbiomed.2026.03.048
Mar 16 2026 -
Rab27-dependent mitochondrial extrusion from dopaminergic neurons drives neuroinflammation and neurodegeneration in the MPTP mouse model of Parkinson’s disease
Author:
Yingqi Xu, Junyu Li, Shanshan Ma, Ting Yang, Ziyue Shen, Mingtao Li, Qiaoying Huang
Journal: Free Radical Biology and Medicine
Doi: https://www.doi.org/10.1016/j.freeradbiomed.2026.01.053
Mar 16 2026 -
An Improved Method for Determining the Infection Titer of Replication-Competent Adeno-Associated Virus
Author:
Jianning Fu, Lei Yu, Zhihao Fu, Guangyu Wang, Chenggang Liang, Xinchang Shi, Yixuan Zhang
Journal: Biomedicines
Doi: https://www.doi.org/10.3390/biomedicines14030653
Mar 13 2026 -
Multi-omic profiling of human and mouse dorsal root ganglia enables targeted gene delivery to nociceptors
Author:
Lily S. He, Parth Bhatia, Shamsuddin A. Bhuiyan, Evangelia Semizoglou, Jiaxiang Wang, Jia Li, Joohyun Nam, Jay X. J. Luo, Chayse Arnhold, Difei Zhu, Mengyi Xu, Dustin Griesemer, Hyo Jeong Yong, Lorna Jayne, Evangeline Gilmer, Qiyi Li, Katerina Pantaleo, Lite Yang, Erika K. Williams, Selwyn Jayakar, Brian J. Wainger, Sinisa Hrvatin, View ORCID ProfileWilliam Renthal, NIH PRECISION Human Pain Network
Journal: BioRxiv
Doi: https://www.doi.org/10.64898/2026.03.05.709931
Mar 12 2026 -
Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle–mediated mRNA delivery in preclinical models
Author:
Kangfu Chen, Wenhan Wang, Amber Lennon, Ryan A. McClure, Aleksandra Vuchkovska, Shana O. Kelley, and Zongjie Wang
Journal: Science Translational Medicine
Doi: https://www.doi.org/10.1126/scitranslmed.adx4097
Mar 11 2026