
About PackGene 
PackGene is a world-leading adeno-associated virus (AAV) vector CRO and CDMO company, providing economical, reliable, and scalable plasmid DNA and AAV viral vector production for early-stage drug discovery, preclinical development and clinical trials for Cell and Gene Therapy (CGT). The proprietary π-Alpha™ 293 AAV High-yield Platform uses uniquely designed RC plasmid in the triple-plasmid transfection system to increase AAV production by 3 to 8 times in various AAV serotypes. With combining both in-process upstream and downstream QbD optimizations, the total AAV yield can be increased up to 10 times. The single batch of AAV production delivers up to 1E+17vg virus particles which can meet the needs of most clinical-level and commercial levels of AAV production.
CRO Services
One-stop Custom AAV Packaging Services

AAV Vector Design

AAV Packaging Services

AAV Analytical Services

AAV Fast Services


CDMO Services
One-stop CDMO Services for GMP Manufacturing

GMP Plasmids Services

GMP AAV Services

AAV Analytical QC Services

Aseptic Fill & Finish
Technology Platforms

π-Omega™ Plasmid DNA High-yield
Production Platform
Increase AAV production by 3 to 8 times in various AAV serotypes

π-Alpha™ 293 AAV High-yield
Production Platform
Increased the plasmid yield by more than 3 times through the plasmid backbone modification

π-Icosa™ AAV Serotype
Screening Platform
Screen higher infective and higher tissue-specific AAV serotypes