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Decibel, Principal Scientist
“A lot of our programs internally have been having great results with the AAV vectors you all have been packaging. PackGene is rapidly becoming our go-to for AAV vectors! ”

Biogen Scientist
“I have spreaded the word of my satisfaction with your AAV vectors to many people in Biogen’s research labs and I hope we continue to be a regular customer in the future.”
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PCDH15 Dual-AAV Gene Therapy for Deafness and Blindness in Usher Syndrome Type 1F
BioRxiv. 2023 Nov 13 Maryna V. Ivanchenko, Daniel M. Hathaway, Eric M. Mulhall, Kevin T. Booth, Mantian Wang, Cole W. Peters, Alex J. Klein, Xinlan Chen, Yaqiao Li, Bence György and David P. Corey Products used in the paper Details Operation AAV vector AAVs were...
Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy
Nature Biomedical Engineering. 2023 Dec 6 Christiano R. R. Alves, Leillani L. Ha, Rebecca Yaworski, Emma R. Sutton, Cicera R. Lazzarotto, Kathleen A. Christie, Aoife Reilly, Ariane Beauvais, Roman M. Doll, Demitri de la Cruz, Casey A. Maguire, Kathryn J. Swoboda,...
Intranasal mask for protecting the respiratory tract against viral aerosols
Nature Communications. 2023 Dec 18 Xiaoming Hu, Shuang Wang, Shaotong Fu, Meng Qin, Chengliang Lyu, Zhaowen Ding, Yan Wang, Yishu Wang, Dongshu Wang, Li Zhu, Tao Jiang, Jing Sun, Hui Ding, Jie Wu, Lingqian Chang, Yimin Cui, Xiaocong Pang, Youchun Wang, Weijin Huang,...
NeuroD1 and Ascl1 Convert Human Glial Cells into Neurons in Ex Vivo Culture of Human Brain Tissue
Research Square. 2023 Dec 14 Liang Xu, Qingsong Wang, Jiancheng Liao, Jiajun Zheng, Bing Qin, Wen Li, Jiaxuan Zhang, Wei Li, Xiangyu Wang, Maoying Zhang, Gong Chen Products used in the paper Details Operation AAV vector packaging Adeno-associated virus (AAV): AAV9...
Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
Neuron. 2023 Dec 20 Ngan Pan Bennett Au, Tan Wu, Xinyu Chen, Feng Gao, Yuen Tung Yolanda Li, Wing Yip Tam, Kwan Ngok Yu, Daniel H. Geschwind, Giovanni Coppola, Xin Wang, and Chi Him Eddie Ma Products used in the paper Details Operation AAV vector packaging...
The Study on PLA-based nano-bio effects and its biomedical applications
. 2023 Aug DING Zhaowen Products used in the paper Details Operation was used as a negative control Request Quote Research Field: Coronavirus Keywords: PLA, nano-bio interfacial interaction, lamella nanomaterial, microsphere AAV Serotype: pseudovirus Animal or cell...
Regulation of myo-miR-24-3p on the Myogenesis and Fiber Type Transformation of Skeletal Muscle
Genes. 2024 Feb 21 Danyang Fan, Yilong Yao, Yanwen Liu, Chao Yan, Fanqinyu Li, Shilong Wang, Mei Yu, Bingkun Xie and Zhonglin Tang Products used in the paper Details Operation AAV vector packaging AAV1-hOTOF was developed by researchers at the Eye & ENT Hospital of...
Enhancing transduction efficiency of adeno-associated virus 9 by cell line engineering: implication for gene therapy potency assay
Biotechnology and Bioprocess Engineering. 2024 Feb 19 Nanyeong Go, Changhyun Ahn & Jae Young Lee Products used in the paper Details Operation AAV vector packaging In brief, mice were intranasally infected with AAV-hACE2 (PackGene Biotech, Guangzhou, China) Request...

PMWC (Silicon Valley, CA, Feb 5-7, 2025)
The Precision Medicine World Conference (PMWC) is the leading annual event dedicated to advancing precision medicine. Since its inception in 2009, PMWC has served as a cornerstone for the healthcare and biotechnology community, fostering collaboration among global...
Advanced Therapies Week (Dallas, TX, Jan 20-23, 2025)
Discover the heart of the cell & gene therapy revolution—a must-attend event where innovation and partnerships drive the future of drug development. With Texas emerging as a key biomanufacturing hub, this January in Dallas is your opportunity to connect with leading...
Advanced Therapies Congress (Philly, PA, Nov 12-13)
Make your mark at the Advanced Therapies Congress in Philadelphia this November, where global leaders in gene and cell therapy, regenerative medicine, and related fields gather for top-tier education, scientific exchange, and networking. Exhibit your product or...
SITC (Houston, TX, Nov 6-10)
Join us at SITC's 39th Annual Meeting, the premier cancer immunotherapy conference, where global leaders from academia, industry, and government come together for cutting-edge education, scientific exchange, and networking. Showcase your product or service to advance...
ESGCT 2024 (Rome, Italy, Oct 22-25)
The ESGCT supports scientists and clinicians in gene and cell therapy, promoting research, collaboration, and awareness. With new delivery vectors and genome engineering advancements, more life-changing treatments are possible. Join us at the Annual Congress in Rome...
Advancing Gene and Cell Therapies for Cancer (Philly, PA, Oct 16-17)
Join ASGCT at the Wyndham Philadelphia Historic District, Oct. 16-17, 2024, for an unparalleled opportunity to immerse yourself in the latest research related to gene and cell therapy for cancer in Philadelphia's vibrant Historic District.Time: Oct 16-17, 2024Address:...
Webinar: Current Challenges and New Approaches to Developing rAAV Manufacturing Processes for Large-scale GMP Production
Abstract:Adeno-associated virus (AAV) production faces significant challenges, including low yields, scalability issues, and inconsistent quality. Scaling up AAV production to meet clinical and commercial demands requires innovative solutions. PackGene's proprietary...
Cell & Gene Meeting on the MESA (ARM; Phoenix, AZ, Oct 7-9)
The 2024 Cell & Gene Meeting on the Mesa is the premier annual conference for industry leaders, focused on innovative research and overcoming commercial challenges in cell and gene therapy. The event features expert panels, networking opportunities, and over 100...

Navega Therapeutics Receives $4 Million CIRM Grant to Advance Epigenetic Gene Therapy for Chronic Pain
SAN DIEGO, CA – February 4, 2025 – Navega Therapeutics, a pioneering biotechnology company developing cutting-edge epigenetic gene therapies, today announced a significant milestone with the receipt of a $4 million Translational Science grant from the California...
Akribion Therapeutics Secures €8 Million in Seed Financing to Advance Novel RNA-Guided Cell Depletion Technology
ZWINGENBERG, Germany, February 4, 2025 – Akribion Therapeutics, a biotechnology company pioneering a unique, RNA-guided, nuclease-based technology for programmable cell depletion, today announced the closing of an €8 million Seed financing round. The round was led by...
UF-Kure19 CAR-T Cell Therapy Demonstrates High CR Rates, Low Toxicity in R/R NHL
Treatment with UF-Kure19, a rapidly manufactured CAR T-cell therapy, led to complete responses (CR) and low toxicity in patients with relapsed/refractory non-Hodgkin lymphoma, according to data from a single-arm, mult-center phase 1 study (NCT05400109) presented at...
Opinion: Companies Vie to Develop a Hunter Syndrome Therapy That Reaches the Brain
Several companies—including JCR Pharmaceuticals, Denali Therapeutics and Regenxbio—have products in the pipeline that could improve treatment options for this rare disease. Hunter syndrome is a rare, X‐linked disease caused by a deficiency of the lysosomal enzyme...
Optimizing AAV Gene Delivery: Hitting the Target Safely and Effectively
The great hope for gene therapy is that one day it will be out of the clinic and into mainstream therapeutics. Bearing enormous potential to treat or cure disease, such technology can replace a defective gene with a healthy one, modulate a disease-causing one, and...
Making Strides Toward Off-the-Shelf CAR T Cell Therapy for Cancer
CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. CAR T cells are engineered cancer immunotherapies that boost or hijack a person’s immune system to target their cancer. To date, all of the approved CAR T cell therapies...
Beacon Therapeutics Achieves Major Milestone with FDA RMAT Designation for XLRP Treatment
Beacon Therapeutics, a pioneering ophthalmic gene therapy company committed to saving and restoring vision in patients with blinding retinal diseases, has announced a significant advancement in its mission. The U.S. Food and Drug Administration (FDA) has...
Allogene Therapeutics Announces FDA Clearance of IND Application for Rheumatology Basket Study
Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company advancing the development of allogeneic CAR T (AlloCAR T™) therapies for cancer and autoimmune diseases, today announced that the U.S. Food and Drug Administration (FDA) has cleared its...
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