Recent advancements in gene therapy have unveiled new possibilities for treating Huntington’s Disease (HD), a neurodegenerative disorder characterized by the progressive decline of motor and cognitive functions. This condition is caused by the expansion of CAG repeats...
The power of CRISPR became definitively clear when the first CRISPR-based gene therapy, Casgevy (exa-cel), won regulatory approvals for the treatment of sickle cell disease. But CRISPR’s applications are not limited to therapeutics. CRISPR has also been used to create...
In a pioneering study published in *Science*, a team of researchers led by Peter H. Yoon and Jennifer A. Doudna from the University of California, Berkeley, has made a remarkable discovery in the realm of CRISPR technology. The team has identified an ancestral clade...
“Everything in the last 14 years of genome editing has been based on CRISPR. We have been whipping this horse for a decade and a half, but we need more programmable functions with complexity beyond the molecular scissors that cut RNA and DNA,” says Patrick Hsu, PhD,...
