How to Select AAVs
Step 1: Determine what specific AAV serotype you need.
At PackGene, we offer the most commonly used AAV serotypes for packaging. Please review Table 1 and Table 2 below as a quick references for during experiment or therapeutic design (the red mark means highly recommended, but majorly depends on your experiment design). In addition, our expert Technical Support team at PackGene would be happy to assist you in the selection of a serotype for your specific needs.
|Liver||Heart||SK muscle||Eye||CNS||CNS (BBB)||Pancreas||Lung||T,B, Dendrital Cell|
Table1. AAV for in vivo experiment
Step 2: Choose the vector fitting your experiments.
- CRISPR-Knock-out (CRISPR-spCas9/saCas9/NmCas9/Cpf1)
- Gene over-expression
- shRNA knock-down