Gene Editing mRNA | PackGene Biotech

PackGene provides a range of mRNA options designed for the expression of proteins that are key to gene editing processes. These include: Cas9 mRNA, Cas9 Nickase, Cre recombinase and others.

Our gene editing mRNAs are predominantly available through on-demand fast services to ensure rapid delivery. The default mRNA is tailored with N1-methyl-pseudo Uridine to counteract innate immune responses.

Key Benefits

Diverse mRNA options

Includes Cas9 mRNA, Cas9 Nickase, Cre recombinase, and more for gene editing.
Fast, on-demand services

Quick delivery to meet time-sensitive research needs
Immune response optimization

N1-methyl-pseudo Uridine to minimize innate immune activation

CRISPR Cas9
SpCas9	Order
SpCas9HF	Order
NmCas9	Order
Cas9 Nickase	Order
SaCas9	Order
SaCas9HF	Order
CRISPR-Cas12a
AsCpf1	Order
LbCpf1	Order
CRISPR-Cas13
PspCas13b, huADAR2DD (ADARB1 Human)	Order
PspCas13b-huADAR2DD (ADARB1 Human) delta-984-1090	Order
CRISPR Gene Regulation
MS2-p65-hHSF1	Order
dCas9-VPR	Order
Cre-LoxP
Cre	Order
Cre-EGFP	Order
Sleeping Beauty Transposon
Sleeping Beauty SB-100	Order
Base Editor
ABE8e_P2A_GFP	Order
ABEmax_P2A_GFP	Order
BE4max_P2A_GFP	Order
AncBE4max_P2A_GFP	Order
Prime Editor
PE2-P2A-GFP	Order
PEmax-P2A-EGFP	Order

Co-encapsulation of sgRNA and Cas9 mRNA for gene editing

72hrs after transduction of SpCas9 mRNA co- encapsulated with sgRNA in LNP at a ratio of 1:1