AAV Production Services
- Fast, high-quality AAV vectors with reliably low empty capsid content
- 70+ serotypes, 40+ QC assays, and precision vector design expertise
- 50,000+ AAV batches delivered; effortless transition to GMP manufacturing
Key Benefits
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Fast Turnaround
Delivery as quick as 7 business days for research grade -
High Quality
Low empty capsids, high genome integrity, endotoxin <10 EU/mL -
Comprehensive Analytical
40+ QC assays including qPCR, ddPCR, SDS-PAGE, TEM, Mass Photometry and mycoplasma/bioburden testing -
Scalable Solutions
AAV production from research-grade to GMP-grade for clinical studies and IND/BLA submission -
Expert Design Support
PhD-level scientists plus piVector™ Designer tools streamline every custom order
Service Details
| PackGene AAV Production Services | |||
|---|---|---|---|
| Research Grade | NHP Grade | HT Grade | |
| Application | Cell culture, small animal | Small animal or non-human primates | Cell culture |
| Scale | 2E+12 ~ 8E+14 GC | 1E+13 ~ 1E+16 | 2E+11 ~ 2E+13 GC |
| Lead time | Start from 12 business days | Start from 17 business days | 7-14 business days |
| QC test | qPCR, SDS-PAGE Coomassie Blue Staining, endotoxin LAL, plasmid restriction enzyme digestion | ddPCR, SDS-PAGE Silver Staining, endotoxin LAL, plasmid restriction enzyme digestion | qPCR |
| Performance Comparison | |||
| Titration | qPCR, Titer meet requirements | ddPCR, Titer meet requirements | qPCR, Titer meet requirements |
| AAV purity analysis | SDS-PAGE, Coomassie Blue Staining, Capsid band size meet reference | SDS-PAGE, Silver Staining, Capsid band size meet reference, Capsid band size meet reference | - |
| Endotoxin Test | LAL, <10EU/mL | LAL, <1EU/ml (endotoxin removal may reach <0.2EU/ml) | - |
| Mycoplasma | - | qPCR, Negative | - |
| Bioburden | - | 48 hr, no growth | - |
| AAV Genome integrity | - | Capillary Electrophoresis, report value | - |
| Empty Capsid | TEM, guaranteed empty capsid rate <30% for common serotypes | TEM, guaranteed empty capsid rate <20% for common serotypes | - |
| TEM images |  |
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Additional AAV QC tests
Performance
Resource
Related Service
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AAV Packaging – Research Grade
- Delivery in as little as 12 days from miniprep to purified AAV virus.
- High purity, low endotoxin levels and minimal empty capsids for reliable performance.
- Access to 70+ serotypes and expert support, backed by 50,000+ successful projects.
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AAV Packaging – NHP Grade
- Endotoxin-free with strict contamination control
- ddPCR-quantified titer and confirmed genome integrity
- Enhanced safety and efficacy with consistent results
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AAV Packaging – HT Grade
- Fast turnaround in as few as 7 business days
- Cost-effective with qPCR-based titer measurement
- Optimized for superior performance in cell culture
