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Custom mRNA-LNP Service

  • Increased stability with protected mRNA delivery
  • Enhanced uptake via optimized LNP formulations
  • Reduced immunogenicity for safer applications
Summer Promotion: Buy One Get One Free
mRNA Services

  • PackGene’s custom mRNA-LNP service provides mRNA encapsulated in your preferred LNP formulation for efficient, stable, and targeted delivery. Our LNP technology enhances mRNA-based therapies and vaccines by improving stability, delivery efficiency, and safety, with customizable options tailored to specific applications.

Custom mRNA-LNP-1
academic promotion

PackGene Referral Program

Refer a friend, get 20% off — and they save 20% too!

Promo Code: New2025
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Key Benefits

  • Increased Stability

    LNPs protect mRNA from degradation, ensuring integrity and effective delivery

  • Enhanced Delivery

    Optimized LNPs enhance cellular uptake and targeted delivery

  • Reduced Immunogenicity

    Reduced immunogenicity minimizes unwanted immune responses

Service Details

Catalog Capping and modification Gene Quantity Timeline(Business days)
mRNA-LNP Custom mRNA Cap1 in LNP Custom gene or off-the-shelf 100μg-20mg 10-25

*Additional time (~2-3 weeks ) for custom gene synthesis

 

mRNA grade and QC standard

QC category QC item Method Specification Research Grade
mRNA-LNP
(On-shelf and Custom)		 RNA Integrity/size Capillary Electrophoresis >80% √
Encapsulate Efficiency Elisa Analyzer Report √
Particle size Dynamic Light Scattering Z Ave. Dia <120nm √
Particle Uniformity Dynamic Light Scattering PDI <0.2​ √
Concentration Capillary Electrophoresis Encapsulated mRNA >0.2mg/mL √

PackGene’s quality control (QC) testing of mRNA lipid nanoparticles (LNPs) includes measurement of various parameters to ensure their quality, safety, and efficacy. Some of the essential QC tests for mRNA LNP are encapsulation efficiency, particle size, and uniformity.

Performance

  • mRNA-LNP performance

    EGFP mRNA (Cap1) -LNP

    mass-distribution intensity-distribution
    Z Ave. Dia (nm) 76.8
    PDI 0.12
    Encapsulation Efficiency 93.91%

  • mRNA-LNP Gene Delivery in Animal

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