Frontiers in Cardiovascular Medicine. 2022 Feb 7
Yong Wu, Zhongxu Luo, Zhengtao Hu, Kun Lv, Yinhua Liu, and Deguo Wang
Yong Wu, Zhongxu Luo, Zhengtao Hu, Kun Lv, Yinhua Liu, and Deguo Wang
Abstract
Background and ObjectivesSpinal cord stimulation can prevent myocardial ischemia and reperfusion arrhythmias, but the relevant neurons and mechanisms remain unknown. Thus, this study applied optogenetic techniques to selectively activate glutamatergic neurons at the thoracic spinal cord (T1 segment) for examining the anti-arrhythmia effects during acute myocardial ischemic-reperfusion.
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