π-Omega™ Plasmid DNA High-yield Production Platform
PackGene’s proprietary π-Omega™ Plasmid DNA High-yield Platform has increased the plasmid yield by more than 3 times through the plasmid backbone modification. The production scale can reach to 200L, and the single-batch production yield can reach to 100 grams. As a key raw material in AAV production, plasmid DNA cost reduction has greatly reduced AAV production cost, while meeting the growingly plasmids demand in the mRNA therapeutic field.
- Greatly reduces cost by two-step chromatography
- High-yield plasmid production through the plasmid backbone modification
- Strain suitable for mRNA plasmid fermentation (maintaining the stability of polyA)
One patents is pending.
Increases Yield about 3-4 times by Molecular Modification on Plasmid
Two-step Purification Process to Improve Plasmid Quality
|Remark||stability||High requirements for upstream stability|
Lower HCD & Higher Recovery Rate
Yield of plasmid maintains in the same range