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mRNA

Cap 1 Fluc (N1meψ) mRNA-LNP LP01

The 306-O12B LNP formulation, containing firefly luciferase mRNA, is developed using a standard LNP formulation with the key ionizable lipid 306-O12B. The cargo, Fluc (N1meψ) mRNA, has undergone full modification of all U bases with N1-methyl-pseudo-uridine. Upon translation, Fluc (N1meψ) mRNA generates firefly luciferase, which emits bioluminescence upon interacting with its substrate, Luciferin. This mRNA sequence is widely employed as a fluorescence reporter in mRNA therapeutics and delivery system development endeavors. This formulation acts as a reliable control for evaluating the suitability of the 306-O12B LNP formulation for your mRNA product in both in vitro and in vivo experiments.

 

LP01

 

SKU: LNPMLUC004

title

content

Gene name

Fluc (N1meψ)

LNP ionizable lipid

LP01

Concentration

0.2 mg/mL

Storage Buffer

5% Sucrose in PBS

ORF length (bp)

1653

mRNA Molecular Weight (kDa)

1653

Storage Temperature

-80°C

Shipping Condition

Dry ice

Handling

Avoid freeze and thaw

Appearance

Clear and colorless

Purity

Fragment analysis by capillary electrophoresis

Base Composition

N1meψ

Capping

Cap1

Stock

On-demand

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