Cap 1 Fluc (N1meψ) mRNA-LNP ALC-0315

Clear
Add to Quote
SKU: LNPMLUC002 Category:

Description

The ALC-0315 LNP formulation, containing firefly luciferase mRNA, is developed using a standard LNP formulation with the key ionizable lipid ALC-0315. The cargo, Fluc (N1meψ) mRNA, has undergone full modification of all U bases with N1-methyl-pseudo-uridine. Upon translation, Fluc (N1meψ) mRNA generates firefly luciferase, which emits bioluminescence upon interacting with its substrate, Luciferin. This mRNA sequence is widely employed as a fluorescence reporter in mRNA therapeutics and delivery system development endeavors. This formulation acts as a reliable control for evaluating the suitability of the ALC-0315 LNP formulation for your mRNA product in both in vitro and in vivo experiments.

ALC-0315

Gene name

Fluc (N1meψ)

LNP ionizable lipid

ALC-0315

Concentration

0.2 mg/mL

Storage Buffer

5% Sucrose in PBS

ORF length (bp)

1653

mRNA Molecular Weight (kDa)

758

Storage Temperature

-80°C

Shipping Condition

Dry ice

Handling

Avoid freeze and thaw

Appearance

Clear and colorless

Purity

Fragment analysis by capillary electrophoresis

Base Composition

N1meψ

Capping

Cap1

Stock

In stock

Additional information