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AAV Library Service

At PackGene, we offer a comprehensive range of AAV library services designed to advance your gene therapy research. Our expertise in AAV library creation and screening allows us to provide solutions tailored to your specific needs, enhancing gene delivery specificity and efficiency while minimizing off-target effects and bypassing innate immune responses.

  • Capsid Library

    Our capsid library services focus on screening novel AAV serotypes to optimize tissue specificity and serotype tropism. Using cutting-edge techniques like DNA shuffling, we generate diverse AAV serotypes that offer distinct advantages in gene therapy applications. This enables us to:

    • Enhance the specificity and efficiency of gene delivery
    • Minimize the risk of off-target effects
    • Bypass innate immune responses

  • GOI Library

    Our Gene of Interest (GOI) library services involve promoter engineering to optimize gene expression and improve promoter tissue specificity. This ensures that your therapeutic genes are expressed at the right levels in the desired tissues, providing:

    • Optimized gene expression
    • Improved promoter tissue specificity

  • Gene Editing Library

    We provide comprehensive Gene editing library services for gene function screening, gene knockdown studies, disease modeling, cancer research, and drug target discovery. Our libraries include custom CRISPR sgRNA libraries, CRISPR activation libraries, CRISPRi libraries, CRISPR knockout libraries and shRNA libraries, enabling high-throughput screening to identify critical genes and pathways involved in various diseases and uncover potential therapeutic targets., facilitating:

    • Gene function screening
    • Disease modeling
    • Drug target discovery
    • Cancer research
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  • Capsid Library
  • GOI Library
  • Gene Editing Library
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Key Benefits

  • Expertise in providing industrial leading AAV packaging service

  • Innovative Techniques such as DNA shuffling, precision mutation or barcoding to handle various library design

  • Success in Serotype Screening

Service Detail

  • Diverse Library Designs

    Diverse Library Designs

  • More library design we can handle

Performance

  • Library quality

    Near 100% coverage of our precision library
    Library-Coverage    		 Excellent library uniformity
    Synthesis-Uniform-1

  • Low mispackaging rates

  • Screening result

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