Ribo Files an EU Phase 1 Application for Its INHBE-Targeting siRNA in Obesity

Oct 07 , 2026
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Oct 7, 2026 —

Suzhou Ribo Life Science and its subsidiary Ribocure Pharmaceuticals have submitted a Phase 1 clinical trial application in the European Union for RBD3133, an siRNA therapy targeting INHBE (inhibin subunit beta E), with overweight and obesity as the intended indication.

RBD3133 is a small interfering RNA (siRNA) designed to silence a specific gene, part of the growing effort to push RNA medicines beyond the liver’s best-established targets. Obesity is an unusually large market for an RNA approach, most of which have focused on rarer, liver-expressed targets.

The filing extends a China-based RNA-therapeutics developer’s reach into Europe and adds to the pipeline of genetic medicines moving toward the clinic.

Source:

https://www.prnewswire.com/news-releases/ribo-submits-european-clinical-trial-application-for-phase--study-of-inhbe-targeting-sirna-rbd3133-302901825.html

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