Encoded Therapeutics Raises $275M to Advance Its AAV Gene Therapy for Dravet Syndrome

Sep 10 , 2026
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Sep 10, 2026 —

Encoded Therapeutics has raised $275 million in a Series F financing to advance its gene therapy for Dravet syndrome, a severe genetic epilepsy that begins in infancy, and to move a second gene therapy candidate toward the clinic.

Dravet syndrome causes prolonged, difficult-to-control seizures alongside developmental delays. Encoded is developing a one-time, adeno-associated virus (AAV)-based gene therapy intended to address the underlying cause of the disease rather than manage its symptoms.

The round was co-led by GV and another healthcare fund, with participation from ARCH Venture Partners, Janus Henderson Investors, and Farallon Capital Management, among others.

Source:

https://www.pharmaceutical-technology.com/news/encoded-secures-275m-for-dravet-syndrome-gene-therapy/

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PackGene Biotech is a world-leading CRO and CDMO, excelling in AAV vectors, mRNA, plasmid DNA, and lentiviral vector solutions. Our comprehensive offerings span from vector design and construction to AAV, lentivirus, and mRNA services. With a sharp focus on early-stage drug discovery, preclinical development, and cell and gene therapy trials, we deliver cost-effective, dependable, and scalable production solutions. Leveraging our groundbreaking π-alpha 293 AAV high-yield platform, we amplify AAV production by up to 10-fold, yielding up to 1e+17vg per batch to meet diverse commercial and clinical project needs. Moreover, our tailored mRNA and LNP products and services cater to every stage of drug and vaccine development, from research to GMP production, providing a seamless, end-to-end solution.

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