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Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2
Author:
Qing He, Zhen Wang, Yuchen Wang, Mengjie Zhu, Zhile Liang, Kanghong Zhang, Yuge Xu, Gong Chen
Journal: Neural Regeneration Research
Doi: https://www.doi.org/10.4103/NRR.NRR-D-23-01897
Jun 2025 -
Regulatory insights on gene therapies, adeno-associated virus-based gene therapies, cell/tissue-based products, and medical care/practice in cell and gene therapies: Report from the 7th Asia partnership conference – April 25, 2024
Author:
Yoshie Tsurumaki, Yusuke Kagawa, Shigeaki Hayashi, Hirokuni Mizoguchi, Masaaki Miyano, Masaki Fujii, Ruriko Shinozaki, Srinivasan N Kellathur, Alex J Zhang, Kunihiko Suzuki, Masayuki Nomura
Journal: Regenerative Therapy
Doi: https://www.doi.org/10.1016/j.reth.2025.02.007
Apr 14 2025 -
Mouse MRE11-RAD50-NBS1 is needed to start and extend meiotic DNA end resection
Author:
Soonjoung Kim, Shintaro Yamada, Tao Li, Claudia Canasto-Chibuque, Jun Hyun Kim, Marina Marcet-Ortega, Jiaqi Xu, Diana Y Eng, Laura Feeney, John H J Petrini, Scott Keeney
Journal: Nat Commun
Doi: https://www.doi.org/10.1038/s41467-025-57928-x
Apr 16 2025 -
A sensory-motor-sensory circuit underlies antinociception ignited by primary motor cortex in mice
Author:
Fei Wang, Zhi-Cheng Tian, Hui Ding, Xin-Jiang Yang, Fu-Dong Wang, Ruo-Xin Ji, Lei Xu, Zi-Xuan Cao, Sui-Bin Ma, Ming Zhang, Ya-Ting Cui, Xiang-Yu Cong, Wen-Guang Chu, Zhen-Zhen Li, Wen-Juan Han, Yong-Heng Gao, Yuan-Wang Yu, Xiang-Hui Zhao, Wen-Ting Wang, Rou-Gang Xie, Sheng-Xi Wu, Ceng Luo
Journal: Neuron
Doi: https://www.doi.org/10.1016/j.neuron.2025.03.027
Apr 15 2025 -
The mechanism of dexmedetomidine regulation of the HIF-1α/FUNDC1 axis in myocardial ischemia/reperfusion injury
Author:
Zhenfei Hu, Yidan Huang
Journal: Histology and Histopathology
Doi: https://www.doi.org/10.14670/HH-18-914
Mar 28 2025 -
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects
Author:
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao
Journal: Advanced Science
Doi: https://www.doi.org/10.1002/advs.202415325
Apr 11 2025 -
Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts
Author:
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin
Journal: Advanced Science
Doi: https://www.doi.org/10.1002/advs.202414830
Apr 15 2025 -
The Role of JPX in Regulating FUS/SLC7A11 Signaling Pathway Mediated Ferroptosis in Keloid Fibroblasts and its Potential in Scar Repair
Author:
Jianhui Tang, Zhaoming Huang, Panpan Yu
Journal: Biochemical and Biophysical Research Communications
Doi: https://www.doi.org/10.1016/j.bbrc.2025.151770
Apr 9 2025 -
Halting hepatocellular carcinoma: Identifying intercellular crosstalk in HBV-driven disease
Author:
Lingyun Zhou, Chang-Hai Liu, Duoduo Lv, Klarke Michael Sample, Ángela Rojas, Yugu Zhang, Huandi Qiu, Linye He, Li Zheng, Liyu Chen, Binru Cai, Yiguo Hu, Manuel Romero-Gómez
Journal: Cell Reports
Doi: https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00228-1?uuid=uuid%3Ac41bdba4-e2a5-46f5-aa90-47ba98d766db#
Mar 30 2025 -
C1QL1 regulates auditory nerve fibers growth via ELMO1-DOCK180-RAC1 integrin
Author:
Minglin Chen,Yue Qi &Shusheng Gong
Journal: Acta Oto-Laryngologica
Doi: https://www.doi.org/10.1080/00016489.2025.2486613
Apr 7 2025 -
Tumor Cell-Derived Exosomal METTL3 Induces Choriocarcinoma Malignant Progression by Targeting Fbxw8
Author:
Wenzhi Wang, Yu Li, Zhuo Deng & Wen Jin
Journal: Bratislava Medical Journal
Doi: https://www.doi.org/10.1007/s44411-025-00111-x
Apr 7 2025 -
Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1
Author:
Kai Lin,Lulu Wei, Ranran Wang, Li Li, Shiyu Song, Fei Wang, Meiwei He, Wenyuan Pu1,2 ∙ Jinglin Wang6 ∙ Junaid Wazir, Wangsen Cao, Xiaozhong Yang, Eckardt Treuter, Rongrong Fan, Yongxiang Wang, Zhiqiang Huang, Hongwei Wang
Journal: Cell Metabolism
Doi: https://www.doi.org/10.1016/j.cmet.2024.10.017
Feb 4 2025