Citations
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Rab27-dependent mitochondrial extrusion from dopaminergic neurons drives neuroinflammation and neurodegeneration in the MPTP mouse model of Parkinson’s disease
Author:
Yingqi Xu, Junyu Li, Shanshan Ma, Ting Yang, Ziyue Shen, Mingtao Li, Qiaoying Huang
Journal: Free Radical Biology and Medicine
Doi: https://www.doi.org/10.1016/j.freeradbiomed.2026.01.053
Mar 16 2026 -
Investigations on the effects of SH2B2 on Parkinson’s disease based on its in vivo and in vitro neurotoxic model
Author:
Lihui Zhao, Ke Han, Lifeng Sun
Journal: Neuroscience
Doi: https://www.doi.org/10.1016/j.neuroscience.2025.12.069
Mar 05 2026 -
Precise and efficient DNA base editing restores normal hearing in adult DFNB9 mouse model
Author:
Ziyu Zhang, Man Wang, Fangzhi Tan, Zuhong He, Renjie Chai
Journal: Med
Doi: https://www.doi.org/10.1016/j.medj.2026.101001
Feb 27 2026 -
An extracellular vesicle-mediated mitochondrial transfer network critical for testosterone synthesis
Author:
Kai Xia, Suyuan Zhang, Hao Peng, Hainan Chen, Cuifeng Yang, Jiajie Yu, Peng Luo, Qiying Lu, Hong Chen, Li Huang, Yifei Xiong, Lerong Zhao, Lei Jia, Lu Li, Yuan Qiu, Yan Guo, Congyuan Liu, Hang Fan, Ziran Dai, Guihua Liu, Qiong Ke, Tao Wang, Weiqiang Li, Lili Chen, Chunhua Deng, Haipeng Xiao & Andy Peng Xiang
Journal: Nature Cell Biology
Doi: https://www.doi.org/10.1038/s41556-026-01896-x
Feb 27 2026 -
Therapeutic base editing alleviates restrictive cardiomyopathy
Author:
Chong Chang, Xiulin Zhang, Xiaoqi Fan, Xiao Chen, Jiangping Song, Xing Chang
Journal: Cell Reports Medicine
Doi: https://www.doi.org/10.1016/j.xcrm.2026.102639
Feb 27 2026 -
B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8+ T-cell response
Author:
Xinyuan Liu, Filiz Demircik, Mariia Antipova, Emmanouil Stylianakis, Matthias Klein, David Bejarano, Abdelrahman Elwy, Anna Ebering, Michaela Blanfeld, Katlynn Carter, Lisa Johann, David C. Uhlfelder, Elisa Blickberndt, Yao Chen, Hans Christian Probst, Nadine Hövelmeyer, Tobias Bopp, Ramon Arens, Lukas Bunse, Joke M. M. den Haan, Jennifer L. Gommerman, Esther von Stebut, Björn E. Clausen, Andreas Schlitzer, Karl S. Lang, Bing Su, Ronald A. Backer, Niels A. Lemmermann & Ari Waisman
Journal: Cellular & Molecular Immunology
Doi: https://www.doi.org/10.1038/s41423-026-01392-0
Feb 24 2026 -
AUF1 therapy blocks atrophy, promotes regeneration, re-innervation and strength for severe muscle injury
Author:
Dounia Abbadi, Olga Katsara, Riley McConnell, Sophie Dornbaum, John J. Andrews, Robert J. Schneider
Journal: Molecular Therapy
Doi: https://www.doi.org/10.1016/j.ymthe.2026.02.033
Feb 23 2026 -
Hyperglutaminolysis drives senescence and aging through arginine-mTORC1 axis activation
Author:
Honghan Chen, Ning Huang, Weitong Xu, Yu Yang, Fangfang Wang, Hui Gong, Jiao Zhou, Haoran Tai, Tingting Zhao, Jian Zhang, Ying Li, Ge Liang, Minghai Tang, Jie Li, Ming Yang, Jin Liu, Xiaoli Huang, Hengyi Xiao
Journal: Signal Transduction and Targeted Therapy
Doi: https://www.doi.org/10.1038/s41392-026-02576-w
Feb 19 2026 -
Telomere recapping via gene therapy as a beneficial strategy for cardio-renal syndrome type 4
Author:
Danshu Xie, Chenguang Wang, Xin Wan, Longyu Wang, Yinlong Zhao, Jianan Pan, Yushu Zhao, Jiaying Ji , Jiaolun Li, Yangyang Liu, Feng Ding, Alex C.Y. Chang, Wei Ding
Journal: Kidney International
Doi: https://www.doi.org/10.1016/j.kint.2026.01.022
Feb 18 2026 -
In vivo base editing of Chd3 rescues behavioural abnormalities in mice
Author:
Kan Yang, Wei-Ke Li, Yi-Xiao Geng, Shu-Qian Zhang, Shi-Hao Wu, Yan-Bo Cheng, Jun-Wen Wang, Zhan-Kui Xu, Wen-Xin Wang, Tan-Ying Zhang, Pei-Ye Wang, Yi-Ting Yuan, Juan Fan, Jun Wu, Ruo-Chuan Xu, Yue-Fang Zhang, Gong-Jia Tao, Zheng-Hui Li, Chen-Xi Lin, Tian-Shu Li, Xin-Yi Zhang, Jie Li, Ru Zhang, Wen-Xiu Yang, Jia-Shuo Wen, Zun-Yuan Yang, Li Gong, Wen Zeng, Ai-Lian Du, Jin-Song Li, Fei Li, Tian-Lin Cheng & Zilong Qiu
Journal: Nature
Doi: https://www.doi.org/10.1038/s41586-026-10113-6
Feb 18 2026 -
FTO mediates m6A demethylation of HNF1A and drives hepatic steatosis in metabolic dysfunction-associated steatotic liver disease
Author:
Jiaorong Tan, Chao Shi, Guangyu Wang, Lijuan Zhang, Fei Li, Guangyue Yan, Yishan Jin, Huiru Ding, Fengxiang Jiang, Xiangqi Li
Journal: Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids
Doi: https://www.doi.org/10.1016/j.bbalip.2026.159732
Feb 12 2026 -
Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission
Author:
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu
Journal: Advanced Science
Doi: https://www.doi.org/10.1002/advs.202519874Digital Object Identifier (DOI)
Feb 12 2026