AAV-CRISPR

Packgene provides pre-made CRIPSR-AAV vectors which base on AAV9 serotype, and cover EFS/miniCMV/CMV broad-spectrum promoters and tissue-specific promoters. Without waiting, our product and can be shipped within the same day when the order is placed on the working day, making it an ideal choice for gene editing experiments.

CRISPR gene editing is a breakthrough after TALEN and ZFN technologies. It uses a gRNA to guide nucleases (such as Cas9) for specific editing of target genes. CRISPR-Cas9 system shows advantages like high editing efficiency, operator-friendly and rich designability. The construction and use of gRNA or Cas9 vectors are now very convenient, and they have been used in gene editing experiments in mammals, plants and other species.
In particular, based on AAV vector, CRISPR-Cas9 or CRISPR-Cpf1 is one of the most widely used gene editing technology, which has come up with many breakthrough discoveries and is gaining increasing recognition in new drug development and clinical research.

Packgene provides Cas9 and Cpf1 vectors packaged with AAV, which can be directly, conveniently and efficiently applied to animal experiments. Each spot product provides a complete quality inspection report.